Tuesday, November 26, 2019

Parenthetical Phrases

Parenthetical Phrases Parenthetical Phrases Parenthetical Phrases By Mark Nichol Let’s say, for the sake of argument, that you’re explaining something in writing such as which punctuation marks to use to signal a break in thought and you want to make it clear to your readers (many of whom may never have realized that there are distinctions to be made). How would you do it? I just did. One of three basic strategies usually suffices to set a parenthetical phrase off from its root sentence. By â€Å"parenthetical phrase,† I mean one that constitutes a digression (or a clarification) and, despite the name, it doesn’t have to involve parentheses. I did it again. You see, the mildest form of parenthesis, for when you want to quickly insert a detail without distracting the reader, is a subordinate clause: a nonessential phrase framed by a pair of commas. The preceding sentence includes a subordinate clause: the one that begins â€Å"for when† and ends â€Å"the reader.† If you temporarily remove that phrase from the sentence, its structural integrity remains intact. (Try it; I’ll wait but don’t forget to put it back when you’re done.) The subordinate-clause parenthesis is one strategy. Another is to use the punctuation characters called parentheses. (The singular form, also used for the compositional device under discussion, is â€Å"parenthesis.†) Notice that I just inserted a parenthesis inside parentheses to make a point that isn’t key to the explanation but provides an additional dollop of information. Note also that I inserted a subordinate clause inside the parenthesis. That’s acceptable but shouldn’t be overdone, because it complicates sentence structure and can obfuscate writing. The third device is the use of what are technically called em dashes so called because they were originally the width of the letter â€Å"m† though most people refer to them simply as dashes. Digression: A pair of en dashes the origin of this name should be apparent are often used in place of em dashes, though they were appropriated from another use. Simple hyphens either a single pair or two doubles also appear in their place, especially online. Why? The hyphen is part of the ASCII roster of basic alphanumeric characters that automatically translate online, but em dashes and en dashes often have to be coded, or they’ll manifest in most browser windows as odd characters; we’ve all seen that error on even otherwise professional Web sites. Therefore, they’re used less often on the Internet. End of digression. Dashes and their substitutes, as opposed to quotidian commas and wallflower parentheses, are best used to call attention to the inserted phrase hey, look at me! and note that often, they are used not in pairs with a parenthetical phrase within, but rather alone, setting a phrase off at the end of a sentence a function commas but not parentheses share. I have allowed these devices to proliferate here for the sake of instruction; but use them sparingly. (Especially, don’t use more than a single dash or a pair of dashes in one sentence or in consecutive sentences, or the passage may be difficult to follow.) Employed in moderation, and when each type is used according to its strength, parenthetical punctuation is a powerful textual tool try it! Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Punctuation category, check our popular posts, or choose a related post below:20 Types and Forms of HumorEmail Etiquette5 Ways to Reduce Use of Prepositions

Saturday, November 23, 2019

Four Common Idioms from Shakespeare

Four Common Idioms from Shakespeare Four Common Idioms from Shakespeare Four Common Idioms from Shakespeare By Maeve Maddox What do the following examples from the Web have in common? Changing my mind  is not something that happens often.  Its a simple case of  me  stating  my  point and  refusing to budge an inch  from it.   US Recovery Cold Comfort for Unemployed Are your kids  eating  you  out of house and home  during the summer? . I made the mistake of buying him an egg salad sandwich, even though  in my heart of hearts I knew  he wouldnt like or eat it. Each one contains a phrase from Shakespeare that is still in widespread use. refuse to budge an inch In the frame story of The Taming of the Shrew, drunken Christopher Sly has been thrown out of an inn. An inn employee threatens to call the law on him, but Sly refuses to be intimidated by the threat. He tells the employee to call whom he will, but that he’ll â€Å"not budge an inch.† Sly uses the expression literally: he will not physically move from the place where he immediately falls asleep. In modern usage, the idiom is usually used figuratively with the meaning, â€Å"stand firm,† â€Å"refuse to change one’s mind on a matter.† cold comfort Shakespeare uses this expression in two plays: The Taming of the Shrew and King John. In the Shrew, Grumio uses the expression in a lengthy and bawdy punning exchange with another servant. In King John, the king, dying of poison, suffers from a burning fever. When his attendants inquire how he feels, he responds hyperbolically, personifying Winter and chiding them for not asking winter: to make his bleak winds kiss my parched lips And comfort me with cold. I do not ask you much; I beg cold comfort; and you are so strait And so ingrateful you deny me that. In modern usage, â€Å"cold comfort† is used figuratively in contexts in which something that is good in one sense is not adequate consolation for those who do not benefit from it. For example, the news of a drop in unemployment is â€Å"cold comfort† to people who remain unemployed. to eat one out of house and home In Henry IV, Part 2, Hostess Quickly of the Boar’s Head tavern has called the law on Falstaff because he has run up an unpaid bill of 100 marks. When the Lord Chief Justice asks for details, she says, â€Å"He hath eaten me out of house and home; he hath put all my substance into that fat belly of his.† In modern usage, the expression seems to be especially common in reference to teenagers. in my heart of hearts Shakespeare puts the expression in Hamlet’s mouth, although without a plural: Give me that man That is not passion’s slave, and I will wear him In my heart’s core, ay, in my heart of heart. Hamlet is praising Horatio for being the kind of man who can be trusted. In modern usage the phrase â€Å"heart of hearts† means, â€Å"the seat of one’s truest feelings.† The expression is especially popular on dating sites. For example: The most important question to ask yourself is this:  In your heart of hearts, do you believe that he or she is the one and only? Happy Birthday, Shakespeare! He was not of an age, but for all time!- Ben Jonson (1572-1637) William Shakespeare Born: April 23, 1564 Died: April 23, 1616 Related posts Shakespeare’s Vocabulary Book Titles From Shakespeare Sources of Titles Drawn from Shakespeare 20 Movies Based on Shakespeare Plays The Most Unkindest Cut of All Thou Lily-livered Boy Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Expressions category, check our popular posts, or choose a related post below:Fly, Flew, (has) FlownFlied?44 Resume Writing Tips7 Proofreading Steps

Thursday, November 21, 2019

BANK OF AMERICA TECHNOLOGY (ATM, ONLINE BANKING, ALL TECHNOLOGY Essay

BANK OF AMERICA TECHNOLOGY (ATM, ONLINE BANKING, ALL TECHNOLOGY ASPECTS) - Essay Example (Frguson, 2000).Many banks are now spending huge amounts of money in technology .This money is being spent not only to update and maintain their IT infrastructure but also to keep ahead of the competition by being the first to provide the latest technologies. Some of the technologies provide ease and convenience to the customers and others help the banks to reduce their overheads and thus save money which was usually spent on physical infrastructure. Technology is also allowing small banks to compete with big established banks as they rely more on their virtual infrastructure than on their physical infrastructure to compete. IT has provided many custom made and off the shelf solutions to take care of their accounting and back office needs. IT has also helped in the development of new channels of reaching out to the customer such as auto teller machines, net banking, mobile banking and various other facilities. Some examples of technology products which are used by banks to provide se rvice to its customers are net banking , credit card online , mobile banking , electronic money transfer , online payment of taxes , mobile recharges , airline ticket booking etc. The list of services being provided by banks to its online customers is endless. Bank of America Corporation as a financial services company is the largest bank holding company in USA by assets and second largest by market capitalization. (Federal Financial Institutions Examination Council, 2009).It was founded in 1874 and was initially known as Nations bank .Its current name was assumed after the acquisition of a San-Francisco bank named as Bank of America. The need of information technology in Bank of America was felt due to another revolution that it has pioneered. It was one of the first banks to deploy branch offices of the parent bank in many locations all across the nation. But cashing a cheuque in a different location was a cumbersome process for the customers

Tuesday, November 19, 2019

Compare and Contrast Country Lovers and The Welcome Essay

Compare and Contrast Country Lovers and The Welcome - Essay Example However, other issues that are related to the study of literary works such as style are usually the same. The thematic concerns that are centered in literary works are also mostly the same. These are the various factors that are discussed when looking at literary works. This paper will be a discussion of two literary works Country Lovers by Nadine Gordimer and The Welcome Table by Alice Walker. Focus will be on content, form, style and setting of the two literary works. These features will be analyzed so as to ascertain the rationalization that they have towards developing the themes of race and ethnicity that are common in both works. All these aspects as pertains to the two stories will be compared and contrasted. Both literary works, Country Lovers and The Welcome Table are short stories. They can be found in a number of collected anthologies. However, despite the fact that they are both story stories, they are quite different. While Gordimer’s story is long and quite detai led, this is not the case in The Welcome Table. This story is quite brief but still manages to pass the message that it was intended to. Through descriptive words, the author has still managed to come up with a plot that is interesting to follow. Therefore, while both literary works are short stories, one is long and much more detailed than the other. This is what contrasts the two literary works of art in terms of form. It also makes them quite interesting to study. ? ­ One aspect that is similar in both Country Lovers and The Welcome Table is the protest about racism; this is followed by the tragic human consequences that this practice comes with. Despite the fact that the stories are written based on the same thematic concerns, the context in which they are written is very different. Moreover, the way in which they are written and the emotional impact that they have on the readers are not the same. For example, whilst Gordimer’s story is written in South Africa when the apartheid regime was rampant, Walker’s story is set in the United States during the post civil war period. These were different historical times that occurred in places that are far apart and the experiences that the characters in this stories had may not have been the same. During the Apartheid system, the law, under the operation of the state was used to impose difficult living conditions on the non-whites in South Africa (Union of South Africa, 2012). This situation can be seen from the text, while Paulus went to school and lived in full comfort and sometimes even enjoying some luxuries, like movies, this was not the same case with Thebedi, she was supposed to do manual labor on the white man’s house with education being a secondary objective to her and the other black children (Gordimer, 1975). This was as per the law that ensured that there was a great disparity between the lives of the blacks and the whites. While this was the situation for the blacks, all wealth , economic and educational opportunities were privileges that were exclusively reserved for the whites in South Africa. On the other hand Walker focuses on the plight that the older rural based African Americans go through. This is through the life of complete slavery that they have been subjected to and they are still subjected to. Even though some reforms were made during the Civil Rights era, there is a lot of subjugation that the blacks

Sunday, November 17, 2019

Existential Lit Final Paper Essay Example for Free

Existential Lit Final Paper Essay Part I 1. In Thomas Nagels â€Å"The Absurd† (1971), he begins by addressing the standard arguments for declaring life to be absurd. The first argument he points out is the idea that nothing humans doing in the present will matter in the distant future, or as Nagel says, â€Å"in a million years† (Nagel 716). People believe that what they do now wont matter at all in a million years, and that they are just one person living in the now that will soon be gone and will therefore not matter and dont matter. Humans see this not mattering as a reason why life is absurd, since if nothing matters then the point of life is questioned. The second standard argument Nagel looks at is the idea that humans â€Å"are tiny specks in the infinite vastness of the universe† (Nagel 717). This idea focuses around space and time, and how individual humans only live for an extremely short amount of time in a tremendously vast universe. People see this as a reason why life is absurd, looking at their lives as such short increments of time, especially on the large scale of the universe. Since humans are so small and take up such little time with their lives, this is seen as a reason life is absurd. The third argument Nagel looks at is about not being able to justifying all of lifes activities, since humans could die at any moment and will eventually. People go through sequences in life, one thing leading to the next, to accomplish something each step of the way, and therefore it is justified. However, eventually, life must end, and the chain of sequences will be cut off in the midst of one of the activities, and therefore will end without justification. â€Å"All of it is an elaborate journey leading to nowhere† (Nagel 717). These are the three standard arguments for explaining why life is absurd that Nagel discusses. Nagel, however, disagrees with these arguments and finds each invalid for specific reasons. When looking at the idea that nothing humans do now will matter in a million years, Nagel objects this with the realization that it doesnt matter now whether or not what we do now in a million years will matter or not. Whether what humans do now will matter in a million years or not is not important, because either way it wouldnt change how people feel now. â€Å"If their mattering now is not enough to accomplish that, how would it help if they mattered a million years from now? † (Nagel 716). If now doesnt matter in the future, than the future must not matter now, and therefore this explanation of why life is absurd is invalid. The second idea, focusing on life being absurd because of how small and short lived humans lives are, is contradicted by Nagels idea that if humans were larger presents in the universe theyre lives would still be just as absurd and that if humans lived for longer, or forever, there lives would just be absurd for that much longer, or even infinitely absurd. This thought of humans as living for such a short amount of time and being so tiny in the universe is clearly not what makes life absurd, even if life is absurd. These facts, if anything, would make humans lives more absurd, if they were larger presents in the universe or lived forever then the absurd would be even larger or last for eternity. Therefore, this is not a valid argument in saying that life is absurd. Looking at the third argument, which focuses on death preventing the justification of human lives and its many sequences, Nagel shows that this idea is actually false as life does not consist of these sequences that all have purposes and continuous justification. â€Å"Chains of justification come repeatedly to an end within life, and whether the process as a whole can be justified has no bearing on the finality of these end-points† (Nagel 717). Many things we do in our daily lives are already reasonable and do not need further justification, such as taking aspirin for a headache, Nagel points out. However, even if someone wanted to further justify any of lifes activities, this further justification would also have to end somewhere, as all things must. â€Å"If nothing can justify unless it is justified in terms of something outside itself, which is also justified, then an infinite regress results, and no chain of justification can be complete† (Nagel 717). All reasoning must end at some point and must be accepted as it is instead of looking at it as incomplete, because if it is looked at as incomplete then reasoning is impossible. With Nagels profound contradictions to these three arguments, he shows that these are not valid reasons to say that life is absurd. 2. Though Nagel discards the standard arguments for stating that life is absurd, he nonetheless says that life can be seen as absurd, just for different reasons than the previous ones discussed. He states that life is absurd because of the clash between humans tendency to take their lives so seriously and the ability of humans to doubt these things which they take so seriously or view them as arbitrary. Humans take their lives seriously, as seen through the idea that many things are necessities for living and that humans actions, such as making choices, are very important. However, humans also are capable of seeing things outside of their lives, which then creates doubt about the things that are taken so seriously. This idea that humans cannot live their live without this seriousness, yet can have a point of view outside of their lives that makes this seriousness doubtful, is why life is absurd. â€Å"It is absurd because we ignore the doubts that we know cannot be settled, continuing to live with nearing undiminished seriousness in spite of them† (Nagel 719). There is a clash between what people think is happening in life and what is truly happening, and because humans are able to have a point of view outside of their own life, they can see what is truly happening and therefore become doubtful of what they think is happening. However, they continue on with what they think is happening, or with this seriousness of life, even with the doubts from seeing what is truly happening. These two viewpoints, one within our own lives and one outside our lives, are both unavoidable yet clash with one another, and this, according to Nagel, is why life is absurd. Nagel states that humans take their lives seriously whether they live in a serious manor or not, and regardless of what their primary concerns in life are. â€Å"Human life is full of effort, plans, calculation, success and failure: we pursue our lives, with varying degrees of sloth and energy† (Nagel 719). Humans can reflect, make choices, question things, and decide what to peruse and what to avoid and who they want to be or become. This alone is signified, but when it clashes with humans ability to think outside themselves and survey this seriousness, it creates absurdity. â€Å"Yet humans have the special capacity to step back and survey themselves, and the lives to which they are committed, with that detached amazement which comes from watching an ant struggle up a head of sand† (Nagel 720). This ability to step back creates these doubts and questions about this seriousness life is taken with, doubts and questions about things that seem so sure before stepping back. Nagel explains: We step back to find that the whole system of justification and criticism, which controls our choices and supports our claims to rationality, rests on response and habits that we never question, that we should not know how to defend without circularity, and to which we shall continue to adhere even after they are called into question† (Nagel 720). According to Nagel, life is absurd not because humans are capable of this stepping back and reflecting on the seriousness of life, but because they then continue with their lives and taking them so serious even after doubts about the seriousness have been identified. 3. Nagel focuses on the idea that humans live absurd lives because of their self-consciousness, and therefore their ability to see themselves as humans and create this clash between seriousness and reality. With this, it can be said that God, all-knowing and self-aware, also lives an absurd life. The mouse Nagel refers to cannot have an absurd life because he is not self-aware, so he does not know he is a mouse and does not have the ability to reflect on this and create doubts about it. God, however, knows he is God and therefore has the ability to step back and have doubts. Being self-aware means that you doubt, and that every justification is doubted. This means that God, self-aware, doubts justifications, just like humans, and has an absurd life with the clash between these. When Nagel describes how the mouses life would be if he was self-aware, he says, â€Å" he would have to return to his meagre yet frantic life, full of doubts that he was unable to answer, but also full of purposes that he was unable to abandon† (Nagel 725). This sentence is applicable to Gods life being absurd, as God has a life full of doubts without answers due to his self-consciousness, but also has great purposes that he is unable to abandon, since he is the higher power that humans rely on. Also, like humans, God cannot refuse this consciousness, because to refuse it would mean he is aware of it, and it therefore he would already be self-aware. Since God cannot escape this self-consciousness, he is trapped, like humans, in this clash between his self-awareness and the seriousness that is taken with it and the doubt that comes with self-awareness where he reflects and doubts all justifications. This makes Gods life absurd, just like humans lives, as he too experiences the clash between self and reality. 4. Nagel stresses that absurdity is one of the most significant things that makes humans humans, and that it is essentially incurable. With this idea in mind, it can be seen that religion cannot cure the feeling of absurdity, and religious people live absurd lives just as all humans do. Humans lives are absurd because they have life goals and strive for things, which is the aspect of taking life seriously, but they also can step back and reflect on things and this causes doubts, which happens regardless of religion. â€Å"What makes doubt inescapable with regard to the limited aims of individual life also makes it inescapable with regard to any larger purpose that encourages the sense that life is meaningful† (Nagel 721). Believing in something larger does not allow escaping to occur, as it can be doubted in the same way that individual life can be. People use a higher being for comfort and to give their lives meaning and justification, however, as pointed out before, justifications end and humans no longer look any further. Moreover, religious people still have the humanistic qualities that all humans do that eventually lead to reflection and doubt. Another way of portraying religious peoples life as absurd just as nonreligious lives is to look at the idea of being self-conscious leading to absurdity and that this is a natural part of being human. â€Å"The only way to avoid the relevant self-consciousness would be either never to attain it or to forget it—neither of which can be achieved by the will† (Nagel 725). Religion does not change this unavoidable self-consciousness, and therefore life it still absurd with religion. The idea of religion is to provide meaning to life, however, if all humans are prone to this inevitable doubt, than this meaning will be doubted in the same way that life without meaning is doubted, or may even be doubted even more and therefore this creates a more significant contradiction, and may mean that religion makes life even more absurd. The gap between seriousness and reality is even larger in a life with religion because life is taken more serious, as there is this idea of more meaning, but still has the contradiction with reflection and doubt, hence a life with religion abets absurdity. Nagels main focus about religion is that it does not cure the feelings of absurdity because, regardless of being religious or not, humans cannot avoid this inevitable doubt of their seriousness, and therefore creating this clash which makes life absurd. â€Å"There does not appear to be any conceivable world (containing us) about which unsettlable doubts could not arise† (Nagel 722). Nagels idea about facing this absurdity is, rather than believing in something higher that gives life a certain meaning that does nothing but encourage absurdity, view life as ironic. He says to â€Å"approach our absurd lives with irony instead of heroism or despair† (Nagel 727). Heroism, as seen in religion, means to value life too much, whereas despair, seen in the depressed or suicidal, means to not value life enough or at all. However, to look at the absurdity of life with irony allows humans to live this contradicting life, aware of this contradiction, but continue to live it without denial, torment, or resentment. In Samuel Becketts Waiting for Godot (1953), this concept of absurdity seen from continuing seriousness even after doubting it is portrayed. Vladimir and Estragon have chosen enslavement to an authoritative figure, Godot, and though they have yet to see Godot or even get confirmation that he will eventually come, they still continue to wait for him. This is the same idea that religion brings to humans, as they can live their lives without signs from God or true meaning from religion, yet they still believe because it gives them a sense of purpose. However, this creates absurdity because, for religious people, they also doubt all of this purpose and meaning they are waiting for, and for Vladimir and Estragon, they doubt Godot will ever come. Towards the end of the play, it is clear that Vladimir has doubt about Godot and has a realization that he has been waiting for a long time and will continue to wait, possibly for eternity. He has this realization and doubt about his seriousness for waiting, yet continues to wait. This clash is what makes Vladimir and Estragons lives absurd, and is the same clash that is seen in religious lives as well. 5. According to Nagel, atheistic existentialists, such as Sartre and Camus, dwell on and blame the fact that God doesnt exist as the reason life is absurd. They believe that without God, our lives lack the meaning which they demand, and without this meaning our lives are meaningless, and therefore absurd. However, Nagel has already pointed out that this is not why life is absurd and that whether our lives have meaning or not does not change this clash between the seriousness which we take our lives and the reality that causes us to doubt the seriousness that is the true creator of absurdity. These atheistic existentialists view absurdity of humans lives as a problem, as something that needs a solution or to be fixed. Camus advice on dealing with this â€Å"problem† of absurdity is defiance. Nagel looks at Camus proposal, and says, â€Å"We can salvage our dignity, he appears to believe, by shaking a fist at the world which is deaf to our please, and continuing to live in spite of it† (Nagel 726). This, of course, will not rid our lives of absurdity, as this is not possible as long as we are self-aware and able to reflect, but Camus believes it will give humans at least a more fulfilled life. Nagel disagrees with these ideas, and says that the absurdity of human lives isnt even a problem at all. He falls back on his idea that absurdity is one of the most significant things that makes us human, and humans lives are only absurd because they posses the ability of a kind of insight that other species do not. â€Å"If a sense of the absurd is a way of perceiving our true situation (even though the situation is not absurd until the perception arises) then what reason can we have to resent or escape it? † (Nagel, 727). Nagel says that it is important that humans are aware of this absurdity, yet do not try to avoid it as it is not possible to do such a thing and one will only dwell on this attempt their entire life. Instead, as mentioned before, Nagel suggests the only way going about absurdity is to approach it with irony. It is important to not let this absurdity become torturous, but is also crucial to not allow it to force an avoidance or attempt to surpass the absurdity. The acknowledgment of the clash between seriousness and reality is important in acceptance and living life in between heroism and despair. If humans can look at their absurd lives with irony, the absurdity will be acknowledged, but will not effect their lives as to cause anything actually problematic from happening. Nagel also states that this absurdity is important because it exposes our human limitations and allows humans to understand these, so there is no reason to try to escape this. Nagels argument helps make sense of these atheistic existentialists works. For example, in Camus The Stranger (1942), the ending is very clear because Camus didnt believe in the idea of approaching absurdity with irony, so he did not end his book like this, and instead ended it with Maurseult approaching the absurdity with the dramatic feeling that Nagel discourages. Maurseult is unable to find irony in his absurd life, and blames Gods nonexistence for his inability to justify morals. It is clear that this happens because these are Camus beliefs, and Nagel portrays these as making a problem out of absurdity that shouldnt be a problem at all. Jean-Paul Sartre, also an atheistic existentialist according to Nagel, falls back on the idea that existence proceeds essence, and in that way humans achieve absolute freedom. However, this idea is contradicted by Nagel when he says that humans are born into absurdity and there is no escaping it, as it would have to have been never attained or forgotten, which is impossible to do if its part of humans from the start. Nagels ideas about absurdity, such that it is unavoidable yet not necessarily a problem, contradict these atheistic existentialists ideas, and he ends with he belief that contrary to what these existentialists say, humans must approach their absurd lives with irony, because if nothing matters, than it wouldnt matter to do anything other than this. Part II a. â€Å"Existentialism Is a Humanism†, by Jean-Paul Sartre (1946), focuses on freedom as the bases of morality. Sartre defends existentialism as being a moral philosophy by contradicting arguments against this idea with his own thoughts. The first idea that Sartre rejects is that which claims existentialism allows people to â€Å"dwell in the quietism of despair† (Sartre 1). In his argument against this he focuses on the concept that existence proceeds essence, where humans first exist before anything else, such as defining themselves. â€Å"Man simply is. Not that he is simply what he conceives himself to be, but he is what he wills, and as he conceives himself after already existing—as he wills to be after that leap towards existence† (Sartre 2). This is what Sartre refers to as the first principle of existentialism. The next idea Sartre argues against is that existentialism is a pessimistic view, however, he says that existentialism actually reflects severe optimism. He gives the example of the way an existentialist looks at a coward and sees him as personally responsible for being a coward, as something he chooses and commits to, which is an optimist way of looking at such a thing. Sartre then looks at the idea of subjectivity, which is argued as a negative aspect of existentialism as it is seen as living a solitude and therefore selfish or egotistical life, and conveys two meanings for â€Å"subjectivism†. One meaning he points out is the freedom of an individual, and the other meaning refers to man unable to further himself beyond human subjectivity. This is a further look at existence proceeding essence, as it shows that humans do not choose being human but they do choose their actions after becoming humans, and by choosing for ones self, one chooses for all humans. This shows, therefore, that existentialists view humans as not individuals whom are selfish, but rather that their actions speak for all humans. The last argument Sartre rejects is that existentialism denies reality and the seriousness of humanity. However, according to Sartre, existentialism is humanist when looking at a fundamental definition of the word. â€Å"Man is all the time outside of himself: it is in projecting and losing himself beyond himself that he makes man to exist; and, on the other hand, it is by pursuing transcendent aims that he himself is able to exist† (Sartre 13). Existentialists believe that there is no human action that doesnt have an explanation, and if an action has an explanation it is human. These ideas portray Sartes position that existentialism is a moral philosophy and that it is a humanism. However, his ideas are not enough to make this statement. He focuses deeply on the idea of freedom and that because humans are free as seen by existentialists, existentialism is a moral philosophy. For existentialism to be completely moral, however, it would have to compliment Sartes idea of freedom with other values, such as charity, kindness, and serving our duty to the world and others, as this is what is truly moral and humanitarian. Complimenting freedom with something else though would take some freedom away and therefore his idea of the moral system being based on freedom is invalid. One example Sartre provides to express this idea of freedom being the basis for existentialism, and the reason it is moral, is about a man facing a moral dilemma. He must choose between either staying with his mother, whom has been abandoned by everyone else in her life and only has this one son left, or leaving her, alone and empty, to go join the Free French Forces. He looks at this as a moral dilemma, however, this is not a moral dilemma because both choices are good. A moral dilemma is one where an individual is faced with two options and picks the one which is good and leaves the other which is not good. However, whether this man stays with his mother or goes to fight for a cause, he is choosing between two goods and therefore is not making a moral decision. Sartre also looks at the idea that existentialism leaves you uncertain and that all moral decisions operate with a degree of uncertainty. This, to an extent, is true, and it is not wise to base decisions on certainty of the future. However, there are actions that are possible, and should be, taken based on their consequences. For example, the question of whether one should push another individual off an enormous cliff seems very certain. It is true that life is uncertain, but there is quite a high chance that that individual, if pushed off the cliff, will fall and die. The immediate and certain consequences seen in life are not mentioned and are ignored in Sartres moral system of existentialism, and therefore is not enough to make this claim. Sartre focuses on this idea that freedom is what makes existentialism a moral philosophy, however, true morality limits freedom, and there is so much more to morality than what Sartre mentions. b. Ivan Ilytch and Meursault both experience an epiphany at the end of their lives, and therefore die as happy men. Both men lived selfish lives, unaware of what life truly was about. They both lived under an idea of what they thought was the right way to live, with Ivan attempting to live a normal life, fitting into society, and Meursault living a life in effort to embody the universe. Both of these life styles were structured and allowed the men to just follow guidelines which they believed was the right thing to do. However, this was selfish as it led to them ignoring the rest of the world, such as their families and other aspects of true happiness. Meursault went through life seeing it as meaningless and therefore claims he believes in nothing. However, the fact that he in so deeply devoted to this meaningless shows that he believes in this meaninglessness. This becomes clear when Meursault is talking to the priest and realizes that his uncertainty was just as strong as the priests certainty about everything, and when he says that the priest was living like a dead man he realizes that it was really him who was doing such a thing. Meursault comes to terms with the fact the he so deeply believes that nothing matters and life is meaningless, and in doing so he looses his temper and becomes emotional and passionate about something for once in his life. This same insight about realizing that life is not so structured and that it is about existing and having fulfillment is seen in Ivan when, as he is laying on his death bed, he becomes aware that there is no goal in life. He spent his whole life chasing something, but finally realizes that this is not what life is about, as he already had things in his life that could have given him fulfillment, such as his family. As he looks at his son and is overcome by this realization, he is finally happy. Meursault also was pursing something in life, that of embodying the universe, but he too sees that this is not what life is about. Soon before he dies, he really sees the world for the first time in his life, the smells and sounds that it holds, and is happy. He even thinks about his mother and shows a side, lacking selfishness, that he had never shown before. With this thoughtfulness, as well as recognizing that nothing matters and there is no meaning, he finally gives himself the fulfillment that life is truly about and feels happiness. c. In Samuel Becketts Waiting for Godot (1953), two men wait for an authoritative figure to appear and convey a message, telling them what to do and what to live for. This is a constant part of society, where humans continue â€Å"waiting† and spend their entire lives hoping the universe will tell them something. The play symbolizes this human waiting and longing for something more in many ways throughout it. Estragon cannot take his shoes off, symbolizing that he is stuck on earth and nothing can be done as he cannot escape. Vladimir looks at his hat, as if to find something in it that tells him something or gives some sort of sign, but finds nothing and continues to gaze at the horizon, which holds hope and something more than this life theyre stuck in. However, as trapped and unhappy as they are, as they even considered suicide, they do not give up hope. In fact, they decide against suicide because they must wait for Godot to come and see what he offers, and then they will decide what to do from there. Vladimir and Estragon cannot stop their wanting to live as they want to live for something, so they are hoping that Godot will give them something to live for, even though he already is just from the hope that he might come. They have lost track of time and are unsure of whether they were here yesterday, as waiting tends to make people lose track of time since it is just what humans do and is inherent in our human condition. In metaphysical time, it is always just now, and waiting is eternal. When two new characters enter the scene, Pozzo and Lucky, the main characters become puzzled. Lucky, who is seemingly not so lucky, carries Pozzos bags for him, but he never puts them down, and he obeys Pozzos every command. Vladimir and Estragon wonder why this is, and why Lucky even puts up with Pozzo. Lucky, however, is not much different from Vladimir and Estragon, as he just seeks authority. He wants this enslavement, where he is told what to do and think and how to live. Vladimir and Estragon have their own symbolic bags that they too refuse to put down, as seen through their choice to continue to wait for Godot, with no one telling them they must wait but it being their own decision to do so and continue to do so. When Vladimir and Estragon find themselves worried that Pozzo wants to get rid of Lucky and leave him behind, it symbolizes that they too are worried of being left behind by Godot. This constant desire for authority is something seen in this play as well as in society, as humans are very frightful of being alone or without someone to tell them what to do or how to live. Though Vladimir and Estragons decision to wait is questionable, it does however give them something to do and comes from a command from authority. As mentioned before, though Godot isnt there, Godot is still ruling over them and gives them the authority that is so desperately sought for. This enslavement to Godot seen in Vladimir and Estragon is actually rather admirable, as it shows their devotion and commitment. The patience seen in their servitude conveys their faith and religious spirit. It brings them hope and a sort of comfort to continue this faith and commitment. When the boy comes the second time to deliver Godots message, Vladimir seems to know that the same thing happened yesterday, and that it will continue to happen, but he still continues to wait. The boy does not tell Vladimir that he will convey his message to Godot and does not give Vladimir his desired recognition that this is real, and Godot has not shown up, yet Vladimir and Estragon still continues to wait and do not lose hope. This idea that they are not just existing as humans but are devoting themselves to this higher authority shows that their existential journey leads beyond existentialism, as they continue to wait by choice but are being controlled by the idea of something more.

Thursday, November 14, 2019

Anne Moodys Coming of Age in Mississippi Essay -- Mississippi Age Com

Anne Moody's Coming of Age in Mississippi Coming of Age in Mississippi is the amazing story of Anne Moody's unbreakable spirit and character throughout the first twenty-three years of her life. Time and time again she speaks of unthinkable odds and conditions and how she manages to keep excelling in her aspirations, yet she ends the book with a tone of hesitation, fear, and skepticism. While she continually fought the tide of society and her elders, suddenly in the end she is speaking as if it all may have been for not. It doesn?t take a literary genius nor a psychology major to figure out why. With all that was stacked against her cause, time and time again, it is easy to see why she would doubt the future of the civil rights movement in 1964 as she rode that Greyhound bus to Washington once again. The events that had occurred to her up to the point of the end of the book could clearly have disheartened anyone. Throughout the novel Moody shows displeasure with her family and fellow black citizens for simply accepting the circumstances and the position in which they lived. Multiple times she refers to the elder blacks as brainwashed by Mr. Charlie, referring to the white plantation owners. She condemns how anytime something clearly unacceptable happens, the black community hushes itself and moves along about their business. This is evident even when she is fourteen years old and just entering high school. Upon the murder of Emmett Till, she questions why was he murdered and what was going to be done about it. Her mother responds to her questions with hostility, and this upsets her more. She wonders why she should remain quite about the incident, pretending she doesn?t know. After learning that Emmett was murdered because he got out of line with a white woman, she questions this rationale. Does that make it OK to murder him? How were his actions any different from how young white me n treated black women? To ask these questions at this point in time were unthinkable to her mother and most anyone else she associated with. She was just a young black girl and should keep her concerns to herself. Moody clearly portrays herself as someone unwilling to accept society in its condition from a very early age, which obviously foreshadows her involvement in the activist?s community. I would argue that the mentality of African-Americans to... ...ndmother would not let her in her house for fear that she might cause trouble! At her mother?s birthday party no one would really speak with her, afraid of what she might say. While her sister and younger brother still respected her, to be shunned by the majority of ones own family would have to be a very traumatic experience. Seriously, how much can one person take on a mission and constantly have little or no success and maintain a positive outlook? Throughout the reading I was amazed and impressed with Moody?s determination and drive. I am thankful that I was not placed in her shoes, because I am not sure that I could have maintained her level of courage or optimism. I feel she has the right to be somewhat questionable towards the end of the book, if not for her own experiences, to encourage anyone who reads her book to never give up on one?s own dreams. With all her doubts, look at all that has been accomplished in the area of civil rights, and what might never have been if not for people like Anne Moody. Bibliography: Moody, Anne. ?Coming of Age in Mississippi.?Literary Cavalcade Apr. 2001 : 31-33. Proquest Kamiakin Library, Kennewick, Wa. 10 May 2001.

Tuesday, November 12, 2019

Literature Review of Selection Methods

Application forms Application forms are one of the most common selection and assessment methods in practice, used almost as much as the CV; most particularly in the public and voluntary sectors (Zibarras and Woods, 2010). Shackleton and Newell (1994) found that out of seventy-three British organisations they surveyed, 93. 2% of them used application forms. Zibarras and Woods (2010) found in a survey they conducted that the use of application forms by organisations were highest in either micro-organisations or very large organisations.The possible reasons for this could be that a very large organisation may receive a lot of applications therefore application forms may be used as a tool to refine the best applicants. In micro organisations the use of an application form could be to find out specific information about an applicant or to see whether they could cope working within such a small organisation. Another point that Zibarras and Woods (2010) recognize is that application forms a long with structured interviews can be defined as standardized selection methods.This could be interpreted as having a higher validity as in an application form an organisation can identify what they want to know about the applicant and then base the questions or the relevant information that is required, and add these into the application form. They also identify that application forms are more ‘legally defensible’. Application forms could be considered more formal, there are guidelines and everything is easy to monitor and pitted against a selection method such as a CV where the applicant has freedom to include what they want the employers to know.Management exercises Management or group exercises are an assessment method typically used within an assessment center. Blume, Dreher and Baldwin (2010) found that management and group exercises were able to assess the critical thinking and the oral communication of an applicant. However, they also found that these exercises like many other of the assessment center tasks involve high communication from the applicant and therefore may be deemed as stressful to some candidates.They go on to identify the importance of show off other skills like organisation and planning when effective oral communication is being assessed. Sackett and Dreher (1982) that when doing any group exercise at an assessment centre the most common skills that are presented through the exercise are leadership, initiative, planning and organisation, problem analysis and decision making, with scores ranging from . 67 and to . 79, the highest with either leadership or initiative.Also from this study, some key behaviours for a manager to possess are not tested very well using this assessment method, these include responsiveness; only scoring . 46, sensitivity; scoring . 47 and stress tolerance; with a score of . 54. Blume, B. D, Dreher, G. F and Baldwin, T. T. (2010). Examining the effects of communication and apprehension within assess ment centres. Journal of Occupational and Organisational Psychology (2010), 83, 663-671. The British Psychological Society. Sackett, P. R and Dreher. G. F. (1982).Constructs and Assessment Center Dimensions: Some Troubling Empirical Findings. Journal of Applied Psychology 1982, Vol. 67, No. 4, 401-410. Shackleton, V, & Newell, S. (1994). European management selection methods: A comparison of five countries. International Journal of Selection and Assessment, 2(2), 91-102 Zibarras, L. D and Woods, S. A (2010). A survey of UK selection practices across different organisztion sizes and industry sectors. Journal of Occupational and Organisational Psychology 2010, 83, 499-511. The British Psychological Society

Sunday, November 10, 2019

Detection and Differentiation of Tomato Cell Death Essay

The lesions, yellowing, abnormal growth, and drying of tomato leaves at the early stage of the plant affect its fruit bearing. This phenomenon is ascribed to cell death which caused primarily of either â€Å"programmed cell death† or as consequences of the plant’s spontaneous response with pathological agents. Although cell death is an integral part of the plant’s development, extraneous loss of the cell results to the aforementioned consequences. Thus, proper regulation of cell death must be done. Since apoptosis and necrosis can possibly occur in plants, the determination of the type of cell death is crucial in the identification of the appropriate technique for its regulation. In this study, sterilized Solanum lycopersicoides seeds will be germinated at 25  °C culture laboratory. Prior to experimentation, the generated cells will be washed and a two-millimolar pyruvate will be added for ATP production. Then, the cells will be exposed to 2. 5 micromolar of oligomycin for ATP depletion. Also, to limit energy generation to cytosolic ATP production cell will be incubated in the 5 millimolar glucose with 2. 5 micromolar oligomycin. After this, cells will be incubated with staurosporine. Meanwhile, the cell death will be analyzed with respect to morphological criteria, intracellular proteolysis, and DNA fragmentation through conventional agarose gel electrophorosis or field inverted gel electrophoresis. While death detection of the cell will be done by means of Enzyme-Linked Immuno Sorbent Assay, ATP measurement will be done through luminometry. Moreover, phosphatidyl serine traslocation analysis will be done by means of Annexin-V-FLUOS technique to be followed by confocal microscopy and fluorescent-activated cell sorting. Detection and Differentiation of Tomato Cell Death Introduction The term â€Å"apoptosis† was derived from a Greek word which literally corresponds to â€Å"falling off† or â€Å"dropping off†, as analogous to abscission to signify cell death as integral part of every organism’s life cycle (Gewies, 2003). In the mid-nineteenth century, it has been noted that cell death occurs in parallel with physiological functions for every multi-cellular organism (Gewies, 2003). In connection to this, in 1964, expert postulated that cell death occurs not accidentally, but rather in a controlled sequence of steps (Gewies, 2003). Meanwhile, cell death is classified either as apoptosis or necrosis based on morphological and biochemical changes undergone by the cell (Schulze-Osthoff, 2008). As such, plasma membrane of the cell may suffer necrosis due to extreme physiological conditions like hypothermia and hypertonic environment (Schulze-Osthoff, 2008). This plasma membrane damage can also be induced by pathological agents and viruses. On the other hand, the cell can incur apoptosis even at normal physiological conditions, thus, often called as â€Å"programmed cell death† or â€Å"cellular suicide† (Schulze-Osthoff, 2008). The â€Å"programmed cell death† involves intricate biochemical processes; pathogens and environmental stresses attack every cell by means of chemical signals. For example, death signals can be originated from malfunction in DNA repair mechanism, cytotoxic drug treatment, ligation of cell surface receptors, and irradiation (Gewies, 2003). In relation to this, plant responses to inhibit pathogenic growth and disease development by means of protective genes activation which in turn, through chemical reactions, kills the infected cells. The cellular death process then is directed by specific signals and independent biochemical processes in every cell (Dickman, Park, Oltersdorf, Li, Clemente, and French, 2001). Hence, understanding the intricacy of cell death requires an intensive knowledge on chemical principles behind apoptotic or necrotic process. Literature Review Apoptosis, on the basis of pathological and physiological conditions, serves a crucial role in the development of multicellular organisms and regulates cell populations in different tissues (Gewies, 2003). Apoptotic processes direct biological processes such as elimination of harmful cells, differentiation, immune system regulation, and homoeostasis (Gewies, 2003). Hence, apoptotic program dysfunction may lead to pathological conditions like viral infections, cancer, and even AIDS (Gewies, 2003). On the other hand, necrosis occurs when the cell’s inability to regulate homeostasis led to the passage of extraneous water and cellular ions into the cell which results to swelling and lysis (Schulze-Osthoff, 2008). As a consequence, the organelles are then exposed to the extracellular fluid. In contrast, apoptosis may arise even at normal cell condition or tissue homeostasis (Schulze-Osthoff, 2008). This involves chromatin accumulation, cytoplasmic and nuclear condensations, cytoplasm and nucleus transformation into apoptotic bodies that encapsulate nuclear material, ribosomes, and mitochondria (Schulze-Osthoff, 2008). While in vivo necrosis results to damaged tissues causing inflammation, the apoptotic bodies formed by in vivo apoptosis are engulped by adjacent ephitelial cells or macrophages (Schulze-Osthoff, 2008). Conversely, the apoptotic bodies formed by in vitro apoptosis undergo â€Å"secondary necrosis† or final swelling and bursting (Schulze-Osthoff, 2008). Every human body has an estimated 1014 cells that are in continuous progress (Schulze-Osthoff, 2008). In fact, hundreds of thousands cells are generated through mitosis in every second but almost equal number suffers apoptosis due to specific tasks and homeostasis regulation (Gewies, 2003). For instance, the elimination of the tail, and the separation of fingers and toes of a tadpole during its metamorphosis are all attributed to cell death (Schulze-Osthoff, 2008). In addition, newly formed or perilous lymphocytes are destroyed through cell death (Schulze-Osthoff, 2008). Furthermore, programmed cell death or PCD has been observed in variety of species such as in mammals, metazoans, nematodes, insects, cnidaria, plants, and even in unicellular organisms (Gewies, 2003). Thus, cell death is scientifically viewed as essential in the functionality maintenance of an organism. Even though plants have the capability to protect themselves from pathogenic invaders through cell death, viral pestilence and antibiotic stressors, most often, are the cause of loss in tomato harvest (Xu, Rogers, and Roossink, 2004). As defensive response, cell death occurs only in the infected sites or termed as hypersensitive response (Morel and Dangl, 1997). Other means of plants’ defense are through cell wall reinforcement, phytoalexin synthesis, and defense-related genes activation (Kazan, Murray, Goulter, Llewellyn, and Manners, 1998). In hypersensitive response, the pathogen is restricted to a specific part of the plant through localized necrotic reactions (Taliansky, Ryabov, Robinson, and Palukaitis, 1998). Significance Researches showed that at some points PCD of plants and animals is similar. As such, jus like animal cells, plant cells generate apoptotic bodies during apoptosis (Greenberg, 1996). Also, DNA fragmentation is both observed in plants and animals apoptosis (Greenberg, 1996). Moreover, antiapoptotic gene, homologous to dad 1, in animal cells was also detected in plant cells (Greenberg, 1996). However, despite these similarities, differences were also noted. For instance, unlike animal cells, plant cells do not exhibit phagocytotic characteristics. In fact, dead cells of the plants may still perform important functions for the whole architectural organization of the plant (Greenberg, 1996). Hence, further exploration on the nature of PCD in plants should be done to gain an intensive understanding on the underpinning principles behind plant cell death. Similarly, yellowing, abnormal growth, and drying of tomato leaves at the early stage of the plant directly affect its photosynthetic activities. These observations are ascribed to cell death which caused primarily of either â€Å"programmed cell death† or as consequences of the plant’s spontaneous response with pathological agents (Greenberg, 1996). Although cell death is an integral part of the plant’s development, extraneous loss of the cell results to the aforementioned consequences. Thus, proper regulation of cell death must be done. Since apoptosis and necrosis can possibly occur in plants, the determination of the type of cell death is crucial in the identification of the appropriate technique for its regulation. Therefore, it is an imperative to determine the possible type of death, under specific physiological conditions, experienced by tomato cells in order to employ the appropriate intervention in regulating cell death. Experimental Design Sterilized Solanum lycopersicoides seeds will be germinated at 25  °C culture laboratory (Leist, Single, Castoldi, Kuhnle, and Nicotera, 1997). Prior to experimentation, the generated cells will be washed and in the absence of glucose, a two-millimolar pyruvate will be added for ATP production (Leist, Single, Castoldi, Kuhnle, and Nicotera, 1997). Then, the cells will be exposed to 2. 5 micromolar of oligomycin for ATP depletion. Also, to limit energy generation to cytosolic ATP production cell will be incubated in the 5 millimolar glucose and 2. 5 micromolar oligomycin concoctions (Leist, Single, Castoldi, Kuhnle, and Nicotera, 1997). After this, cells will be incubated with staurosporine or STS, a cell death inducer. Meanwhile, the cell death will be analyzed with respect to morphological criteria, intracellular proteolysis, and DNA fragmentation through conventional agarose gel electrophoresis or field inverted gel electrophoresis (Leist, Single, Castoldi, Kuhnle, and Nicotera, 1997). While death detection of the cell will be done by means of Enzyme-Linked Immuno Sorbent Assay or ELISA of Roche Technology, ATP measurement will be done through luminometrical technology of Boehringer Mannheim Biochemicals (Leist, Single, Castoldi, Kuhnle, and Nicotera, 1997). Moreover, phosphatidyl serine or PS traslocation analysis will be done by means of Annexin-V-FLUOS technique to be followed by confocal microscopy and fluorescent-activated cell sorting or FACS analysis (Leist, Single, Castoldi, Kuhnle, and Nicotera, 1997). Cell Death Detection and Differentiation The following instrumental techniques will be utilized in this study for the detection of tomato cell death, and for the apoptotic and necrotic death differentiation. Agarose Gel Electrophoresis of Nucleic Acids Nucleic acids are nucleotide polymers joined by diester bonds of the sugar units (Devor, 2005). These linkages between nucleotides give a negative overall charge to the nucleic acid polymer. Molecules with net electrical charges move predictably under electrical field. Hence, when nucleic acids are subjected to semi-solid gel matrix, they move toward the positive pole (Devor, 2005). In an agarose matrix, the mobility of nucleic acids can be formulated by treating its viscosity as gel density with respect to its entire length (Devor, 2005). This migration is then expressed as a negative exponential function of the radius of nucleic acid (Devor, 2005). ELISAPLUS Cell Death Detection ELISAPLUS is a one-step colorimetric technique of detecting cell death. It can differentiate necrosis from apoptosis with relative quantification (Roche Applied Science, 2007). This can be done without cell staining. ELISAPLUS can be utilized for culture supernatants, plasma, lysates, and serum (Roche Applied Science, 2007). About three hours after induced apoptosis, histone-complexed DNA fragments can be detected through immunochemical method (Roche Applied Science, 2007). On the other hand, the histone-complexed DNA fragments are determined directly in the culture supernatant (Roche Applied Science, 2007). Annexin-V-FLUOS Annexin-V-FLUOS, employed for microscopic and cytometric analysis, is done by means of direct fluorescence staining (Roche Applied Science, 2007). This technique can differentiate necrotic from apoptotic cells and typically used for apoptotic detection of membrane-altered cells especialy in PS-translocation (Roche Applied Science, 2007). In line with this, freshly isolated cells and suspension or adherent cell lines are the appropriate samples for this test (Roche Applied Science, 2007). As such, the PS of the cell surface and necrotic cells are stained by FLUOS or green dye and Annexin-V-Alexa or red dye respectively (Roche Applied Science, 2007). Lastly, about 15 minutes after induced apoptosis, determination test is already done (Roche Applied Science, 2007). References Devor, E. J. (2005). IDTutorial: Gel Electrophoresis. Integrated DNA Technologies. Retrieved March 6, 2009, from http://www. idtdna. com/Support/Technical/TechnicalBulletinPDF/Gel_Electrophoresis. pdf Dickman, M. B. , Park, Y. K. , Oltersdorf, T. , Li, W. , Clemente, T. and French, R. (2001). Abrogation of Disease Development in Plants Expressing Animal Antiapoptotic Genes. Proceedings of the National Academy of Sciences, 19, 12, 6957-6962. Gewies, A. (2003). Introduction to Apoptosis. Apo Review. Retrieved March 6, 2009, from http://www. celldeath. de/encyclo/aporev/apointro. pdf Greenberg, J. T. (1996). Programmed Cell Death: A Way of Life for Plants. Proceedings of the National Academy of Sciences, 93, 12094-12097. Kazan, K. , Murray, F. R. , Goulter, K. C. , Llewellyn, D. J. and Manners, J. M. (1998). Induction of Cell Death in Transgenic Plants Expressing a Fungal Glucose Oxidase. Molecular Plant-Microbe Interactions, 11, 6, 555-562. Leist, M. , Single, B. , Castoldi, A. F. , Kuhnle, S. , and Nicotera P. (1997) Intracellular ATP Concentration: A Switch Deciding Between Apoptosis and Necrosis. Journal of Experimental Medicine, 185, 1481–1486. Morel, J. B. and Dangl, J. L. (1997). The Hypersensitive Response and the Induction of Cell Death in Plants. Cell Death and Differentiation, 4, 671-683. Roche Applied Science. (2007). Apoptosis, Cell Death and Cell Proliferation, 3rd ed. Mannheim, Germany: Roche Diagnostics GmbH. Schulze-Osthoff, K. (2008). Apoptosis, Cell Death and Cell Proliferation, 4th ed. Roche Applied Science. Mannheim, Germany: Roche Diagnostics GmbH. Taliansky, M. E. , Ryabov, E. V. , Robinson, D. J. and Palukaitis, P. (1998). Tomato Cell Death Mediated by Complementary Plant viral Satellite RNA Sequences. Molecular Plant-Microbe Interactions, 11, 12, 1214-1222. Xu, P. , Rogers, S. J. and Roossink, M. (2004). Expression of Antiapoptotic Genes bcl-xl and ced-9 in Tomato Enhances Tolerance to Viral-Induced Necrosis and Antibiotic Stress. Proceedings of the National Academy of Sciences, 101, 4, 15805-15810.

Thursday, November 7, 2019

Protection Of The Uncrc Children And Young People Essay Essay Example

Protection Of The Uncrc Children And Young People Essay Essay Example Protection Of The Uncrc Children And Young People Essay Essay Protection Of The Uncrc Children And Young People Essay Essay In every portion of the universe, kids are peculiarly vulnerable existences therefore they should be in contained of every rights that recognize their demand for protection and harboured off from any knowing and unwilled injury. Littlechild ( 2000 ) construe child protection as kids necessitating proper protection from their provinces and agents, because they are non up to power in protecting themselves. It is cardinal kids should be nurtured in a safe and healthy environment, profiting them in all countries of development and future advancement. Siraj-Blatchford and Woodhead ( 2009 ) shared, a kid s advancement and success in life depends chiefly on the earliest experiences of a kid s acquisition. It is the duty and responsibility of attention of the stakeholders to safeguard kids by making a positive and antiphonal environment for them. ODonnell and Seymour ( 2004 ) analysed issues of kids s disadvantages in unfavorable state of affairss are due to economic factors, poorness, societal values, norms and traditions. These hardships put kids at interest of instruction disadvantages and damage in facets of physical, rational and social-emotional development. These accordingly escalate later in life to unemployment, force, offenses, hapless lodging, hapless wellness and unwellness hence shortening lives and hapless rearing accomplishments to supply for the younger 1s. Davis ( 2011 ) identified these conditions persist from childhood to maturity and transmit across one coevals to another. He added that intercession services are needed for these people so as they can break supply and fit themselves with common necessities and interrupt the rhythm of poorness. Laming ( 2009 ) acknowledged the same to protect kids at hazard and actions to be taken at soonest. It is necessary for stakeholders with authorization to disrupt the concatenation of negative effects by puting early and intensively in kids s rights and well-being. Sketching UNCRC, Britto ( 2012 ) noted it has incorporated 54 articles, categorized into three focal points: cardinal rules, human-centered rights, and agencies of supervising the convention. Lundy, McEvoy and Byrne ( 2011 ) suggested countries in human-centered rights which kids should be entitled on are instruction, drama, privateness, wellness and health care every bit good as equal criterion of life and protection from harmful influences. UNCRC establishes on three chief Fieldss of kids s rights: protection, proviso and engagement ( Leer, 2009 ) . In Winter ( 2011 ) , Alderson ( 2008 ) exemplified an penetration to each field. He addresses on protection ( in signifiers of maltreatment, injury, development, disregard and force ) , proviso ( of services, support, counsel and information ) and engagement ( whereby kids being to the full involved in household, cultural and societal life ) . UNCRC aims to assist kids in meeting necessity basic demands and spread outing chances that re aches out in developing kids s full potency. In making so, UNCRC brings a community together in making a protective environment for their kids. Saffigna et Al ( 2011 ) noted elaborateness in specifying every kid s experience of community as all of them differ. Bronfenbrenner s ( 1979 ) ecological systems theory identifies a kid is influenced indirectly and straight by five crossing systems. These environmental factors can be people, vicinity, place, traditions, schools, civilizations, Torahs, services, policies, ministries and relationships. Woodhead ( 2006 ) detailed with microsystems being closest to child, mundane scenes normally home and school, and relationships with people in at that place. Mesosystems are interrelatednesss between microsystems, exosystems refer to strong influences moving indirectly on the kid such as local authorities, public assistance services and constabularies, and last but non least, macrosystems acknowledge the interceding influence of dominant beliefs and values around kids ( Woodhead, 2006 ) . Pulling from at that place, the UNCRC is logically to be field in the outermost bed of the ecologic al system theory as Vaghri et Al ( 2011 ) defined, articles 42-45 of the Convention accedes in helping province parties to better comprehend, administer and supervise the execution of UNCRC in their several states. UNCRC influences the composing of society s image on kids, early childhood and the patterns. They increase awareness all over the universe to supply a just level playing field for protecting kids from disadvantages ( Siraj-Blatchford, 2009 ) . Article 4 of the Convention on the Rights of Child ( UNCRC, 1989 ) adjure authoritiess in set abouting all appropriate legislative, administrative, and other steps to guarantee kids achieves equality, receives protection and the rights to survival and development in all countries. The convention requires authoritiess set abouting all steps to greatest extent refering to their available resources following with UNCRC. For case plighting kids s rights to the fullest potency of mental and physical wellness ( Fortin, 1999 ) . Harmonizing to Welbourne ( 2002 ) by Shier ( 2001 ) , it is compulsory that all authorization and organisations signer to the UNCRC ought to be committed in doing them portion of their Torahs and to guarantee that their patt erns should be all clip consistent and conforming with the criterions set on protecting the rights and intended benefit of kids. Mekonen ( 2010 ) derived province parties attempts in run intoing the convention s duties to kids reflect kids s significance on their policy dockets hence is making a child-friendliness province. This indicates UNCRC s power to drive on province parties on to take on different positions and positions in doing differences to better quality public assistance for best involvement of kids. That being said, there remain concerns of to what extent does UNCRC protect kids and doing differences in their lives. Across to the Committee on Rights of the Child ( 1989 ) , articles covering specifically on the protection of kids comprises of extended countries. The focal point countries decided upon on are: child labor and instruction. The programme portions how UNCRC was good to the kids who fall through the clefts in Paraguay. Article 32 of the CRC commits province parties in protecting kids from economic development and labor that is prone to risky or intervention to kids s instruction and overall development. Childs who are actuated to labors are derived of chances, development and childhood ( Dukess, 2006 ) . Poverty is a possible cause that drives kids to labor ( UNICEF,2012 ) . To interrupt the rhythm, it is to guarantee kids acquire entree to go to school and have a quality instruction. In Paraguay, UNICEF ( 2007 ) analysed that in 2001, there were 1 in every 5 kids who were economically active, some beginning at an early age and those working daily shown poorer academic consequences. Searching for efforts to eliminate child labor in these communities, the authorities initiated Abrazo Programme in 2005 based on the methodological analysis developed by UNICEF ( UNICEF, 2010 ) . ESC ( 2010 ) briefed Abrazo Programme as a cover that provides attention and attending, such as healthcare entree, instruction support and other benefits for kids and their households. It is inclusive of fiscal support via conditional hard currency transportations. This policy instrument renders hard currency transportations straight to families, nevertheless as programme s demand, parents are expected to direct their kids to school in return ( Fors, 2012 ) . Bing portion of the Abrazo Programme, Cabrera ( 2010 ) noted that presences of community Centres in the vicinities are safe oasiss for kids. Supplying them with instruction supports, resort areas, tiffin and societal aids. Children have entree to instruction and are provided with one healthy repast per twenty-four hours. The Social Welfare Institute contributes nutrient supplies, profiting kids with necessary nutrition yet besides making occupations for female parents fixing repasts. Children from other schools are welcomed to the Centre after their categories, therefore instances of kids confronting maltreatment and development on the streets becomes less likely. Though instruction is an important factor in footings of enriching kids s life-long accomplishments to future battle ( Mekonen, 2010 ) , qualities of instruction Centres are critical tools to kids s acquisition, incorporating: instructors, lessons, resources and stuffs. Rivkin, Hanushek and Kain ( 2005 ) highlighted that instructors effectivity determines school s quality. To engage and retain instructors, the Houston Independent School District ( 2008 ) established the Abrazo New Teacher Induction Program supplying grade-level preparations and mentoring for get downing instructors with the veterans. Expanding the construct, they work together towards a new strategy compromising of professional development preparations for all instructors. Though workshop chances and community support groups for upgrading, fiting instructors with better cognition and patterns in schoolrooms. The plan ensures instructors acquisition and instruction in changeless improvement in order to supply fruitf ully for kids. Teachers are necessities for schools operation, therefore the importance on their quality. Dale ( 2004 ) analysed to get phenomenal transmutation experiences ; these results have to travel through applaudable interagency packages with appraisal and proficient professionals. Paraguay raises profiles of kids s rights significantly with support and counsel of UNCRC. As poorness is a major challenge to child exposure, the Abrazo plan was formed intended to cut down poorness in the long tally to better lives of kids. Although it benefitted Paraguayans, there is deficiency of accurate statistics that track advancement on kid labor. Explained by Joleby and Konstadinidis ( 2008 ) the trouble faced while collating findings was some kids were neer registered in Paraguay s records, whereas UNICEF merely provided general expression with no specific informations. To measure phenomenon of UNCRC, Mekonen ( 2010 ) discerned it is measured by the province parties attempt of inputs that they channelled for the benefit of kids and results they achieve. It is more helpful if stakeholders within provinces are in concurrence with the UNCRC and drama by the Torahs and policies in achieving kid s wellbeing. Noted by Axford ( 2008 ) , anything that contributes to the development and nutriment of kid s well-being and growing plays a function: these involve the whole Bronfenbrenner s Ecological System. Despite committedness of multisectoral schemes and programs of actions, attacks to protect and up convey a kid is to wide extent depending on the health professionals in the microsystem as they have closest interaction with the kid. The health professionals behavior, imparted cognition, traditions and civilizations affect their patterns with kids. Hence, ODonnell and Seymour ( 2004 ) determined that it is significant for frontline staffs to be equipped wi th the accomplishments in acknowledging and cognizing how to react to kids in demand. The UNCRC Acts of the Apostless as a push factor for people to hold more consciousness on the importance of early childhood and encourages stakeholders to put in early childhood sector. As discussed before, puting in early childhood interruptions poorness in distant hereafter. Children are more competent of success in life through good wellness and nutrition, and quality instruction programmes with appropriate stimulation and interaction with others ( The World Bank, 2011 ) . The UNCRC advocates encouragement and support for states to put in the hereafter work force booming the lives of kids coevals after coevals as a society.

Tuesday, November 5, 2019

Email Matters

Email Matters Email Matters Email Matters By Maeve Maddox The ease of dashing off an email is both a convenience and a deadly snare. Emails are not as public as a Twitter tweet, but can lead to grief for the unwary. We’ve all heard the horror stories of the jokester who says something outrageous intended for the eyes of a friend, and then hits the â€Å"Reply All† button by mistake. Because there’s always the chance that an email might go astray, the best practice is what I call the â€Å"Klingon rule†: Don’t say anything in an email that you don’t want a third party to read. (I think it was General Chang in StarTrek VI who said he never uttered anything he wouldn’t want to be overheard. Klingons are always under surveillance.) One way to avoid embarrassing situations with clients or employers is to make a habit of treating every email with care, even the ones you dash off to your friends. Human frailty being what it is, there’s probably no way to avoid saying or typing something stupid at some time or another, but a few tips can save some embarrassment. Common courtesy is the key to writing an email that won’t come back to bite you. Courtesy when writing an email means considering such things as the fact that not everyone can read tiny type or understand texting abbreviations. Depending upon the recipient, sloppy English or attempts at humor can prove deal breakers. In these tippy-toe times of political correctness, it doesn’t take much to offend some people. No one, however, is likely to take offence at standard usage and conventional formatting. Email Address A snappy email handle may amuse your friends, but if you use your account for business as well as social correspondence, you may want to avoid choosing a handle like redhotpapa or partygirl. As the first thing the recipient sees, it can affect the spirit in which the message is received. Subject Line Put something meaningful in the subject line. Be as specific as possible, even for your friends. Instead of â€Å"Hi† or â€Å"Hello,† type something that refers to the message. No one enjoys having to sort through hundreds of emails in order to double check one of them. Font Leave the fancy script and colored text for homemade greeting cards. Choose an easy-to-read font and a dark font color. Dark blue is all right, but black is better. Red is the hardest color to read. Big is better than small. Use a minimum of 12-point. Upper- and Lower-case Use lowercase type with capitals where capitals are called for. Lowercase is easier to read than all caps, but don’t go to extremes and omit capitals altogether. Friends may not mind, but a business colleague may interpret lack of capitalization as evidence of lack of education or energy. Spelling Spell correctly. Use conventional abbreviations. Save texting code for texting. Punctuation It’s easy enough to misinterpret a written message. Reread what you have written before hitting Send. See if the addition of a comma or other punctuation might make your meaning clearer. Salutation Begin your email with the recipient’s name. For a friend or associate, the first name is the obvious salutation. Otherwise, use the full name. I don’t often see â€Å"Dear So-and-So† in electronic correspondence; beginning with the name alone is sufficient. Close The way you end your email will depend upon your relationship with the recipient and the nature of the email. If you are reporting bad news or responding to it, you’re not going to close by writing â€Å"Cheers† or â€Å"Have a nice day.† Here are some options: Best, Best regards, Best wishes, Cheers, Cordially, Kindest regards, I remain yours truly, Regards, Sincerely, Take care, Thanks again, Warmest regards, Yours. If you have asked someone to do something time-consuming for you, your close can be even longer: Thanks for your time and consideration. Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Business Writing category, check our popular posts, or choose a related post below:Definitely use "the" or "a"50 Idioms About Roads and PathsCharles's Pen and Jesus' Name

Sunday, November 3, 2019

Nure health-related website Essay Example | Topics and Well Written Essays - 500 words

Nure health-related website - Essay Example It is quite easy to locate the website using Google as the search engine. By just typing ‘health.gov’ on the browser, the website is the first to be generated. The website domain is ‘gov,’ which can be interpreted to mean that the website belongs to a government-affiliated agency. Actually, it belongs to the US Department of Health and Human Services. Further, the website is under the coordination of the Office of Disease Prevention and health Promotion, the Office of the Secretary and the Office of the assistant Secretary of Health in the US Department of Health and Human services. This website in every respect deals with matters relating to health. The universal resource locator (URL) for the website is http://www.health.gov/. www.health.gov is an outstanding website that commands a lot of authority hence its credibility. Being owned by the Department of Health and Human Services, it is expected that it will abhor the most credible information that is obtained from reliable sources. The government conducts health surveys as well as credible independent surveys, which form the basis of some of the information that is posted in this website. In addition, any health related communication from the government and stakeholders in the health sector are provided through this site. In this regard, the site has diverse health news and resources from different credible sources. The focus on the site is on matters related to human health. This demonstrates that the site is quite specific and objective. Navigating through the site is quite easy because there are different categories that one can click, hence providing an easy access to various form of health information. The site does not collect any personal informat ion unless the user opts to do so though the information is protected. However, non-personal information is collected and saved. The site prohibits sharing, disclosing or selling of its information unless provided by the Federal

Friday, November 1, 2019

Describe how nurses can become more broadly involved with influencing Essay

Describe how nurses can become more broadly involved with influencing health policy related to this childhood obesity. Include resources available in child hood obesity - Essay Example Since a nurse’s profession is related to health and well being of a person, they can guide the health policy makers in a right manner A nurse has knowledge about the growing stage of a child and knows what is needed and what is not needed by a child in terms of food and physical activity. As Per (Nurses together,2012)â€Å"The primary concern related to childhood obesity stems from the fact that obese children tend to grow into obese adults, with the host of associated health problems†. Actually the nurse can help the policy makers understand the inadequacy in the food consumed by obese kids and give an alternative for that with less calorific and more nutritional food. The nurse can inspect whether the policy makers have included the right physical activity requirement for the child. The activity must be appropriate for the child and not burdensome.In order to prevent upsurge in child obesity, nurses must suggest the policy maker to motivate the schools in persuading children to eat healthy food and accept a healthy living style. ANA.Fighting Childhood Obesity Taking a stand to control an epidemic one child at a time (2010). In nursingworld.org. Retrieved June 17, 2012, from